Welcome to the registration page of the
4th MOSBRI scientific conference
 
4th MOSBRI scientific conference
June 10-13, 2025
 
 
Tuesday, June 10, 2025
Welcome coffee
1.00 pm-2.00 pm
Opening/Welcome (Patrick ENGLAND)
2.00 pm-2.15 pm
Macromolecular assemblies : architecture, energetics and dynamics
2.15 pm-6.30 pm
Chairs: Francesca Cutruzzola, Sapienza University of Rome, Italy - Valérie Belle, Aix-Marseille Université, France
1
2.15 pm

Biophysical insights into SHMT non-canonical roles: from RNA interactions to the de novo thymidylate synthesis complex

Sharon Spizzichino
Dept. of Biochemical Sciences, Sapienza University of Rome, Rome, Italy
2
2.40 pm

Understanding clathrin assembly through cryo-electron microscopy structures of clathrin cages assembled in the absence of adaptor proteins

Corinne Smith
School of Life Sciences, University of Warwick, Coventry, United Kingdom
3
2.55 pm

Characterization of Rabies virus phosphoprotein thermoresponsive liquid-liquid phase separation

Caroline Mas
Université Grenoble Alpes, CNRS, CEA, EMBL, ISBG, 38000, Grenoble, France, Grenoble, France
4
3.10 pm

VDAC2-mediated Bax membrane insertion: A structural and functional study

Varun Ravishankar
Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM), Aix-Marseille University, CNRS, Marseille, France Laboratoire de Bioénergétique et Ingénierie des Protéines (BIP), Aix-Marseille University, CNRS, Marseille, France
5
3.25 pm

Unveiling the effect of phosphorylation on the structural and aggregation properties of DPF3a an amyloidogenic intrinsically disordered protein

Tanguy Leyder
Chemistry, UCPTS, CPB lab, Université de Namur, Namur, Belgium
6
3.40 pm

Phase Separation in Biology, Aging & Disease

Thom Leiding
CEO and Founder, Labbot, Sweden
0
3.55 pm

Coffee break


7
4.30 pm

Ex-vivo structural biology: toxic protein species in systemic amyloidosis

Stefano Ricagno
Université de Milan, Milan, Italy
8
4.55 pm

Insights into a colorimetric metalloprotein - Purple Acid Phosphatase and the origin of color in Iron containing proteins

Aishwarya Venkatramani
University of Cambridge, Cambridge, United Kingdom
9
5.10 pm

Unveiling Hidden Insights: Enhanced Analytics with New Heights of Sensitivity

Christophe Quétard
PhD, Field Application Specialist BioAnalytics, Sartorius, Dourdan, France
10
5.20 pm

Revealing surfaces and solvent interactions of macromolecular assemblies by solid-state NMR analysis

Patrick Van Der Wel
Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands
11
5.35 pm

A PDZ tandem repeat folds and unfolds via different pathways

Valeria Pennacchietti
Università La Sapienza, Roma, Italy
12
5.50 pm

Taylor Dispersion Analysis for Amyloid-Beta Peptides Aggregation: A Novel Tool in Alzheimer’s Research

Joseph Chamieh
IBMM - University of Montpellier, Montpellier, France
13
6.05 pm

Enzymes from Neisseria gonorrhoeae and Escherichia coli important during infection

Sofia R. Pauleta
Microbial Stress, Dept. Química, NOVA FCT, UCIBIO-NOVA, Caparica, Portugal
14
6.20 pm

Insights into ultracentrifugation and flow cytometry for the separation and characterization of small particles

Lutz Ehrhardt
Market Development Manager Centrifugation, Global marketing at Beckman Coulter Life Sciences, Villepinte, France
1st Poster session
6.30 pm-8.30 pm
Conference cocktail
7.15 pm-10.00 pm
Wednesday, June 11, 2025
Welcome coffee
08.30 am-09.00 am
Macromolecular engineering and structure/function studies
09.00 am-1.05 pm
Chair: Gregor Anderluh, National Institute of Chemistry, Slovenia
15
09.00 am

Designed macromolecular assemblies for in situ delivery of therapeutic proteins

Andreas Plückthun
Dept. Biochemistry, Universität Zürich, Zurich, Switzerland
16
09.40 am

Scaffold-derived peptides as protein-protein interaction (PPI) inhibitors to target the AuroraA/N-Myc complex in MYCN-amplified neuroblastoma

Simone Rossi
Institut des Sciences Analytiques - UMR5280, Université Claude Bernard Lyon 1, Villeurbanne, France
17
09.55 am

Lego-like peptide assembly of honeycomb multichannel nanofibrils

Francesca Mazzotta
Physical Chemistry of Polymers, Max Planck Insitute for Polymer Research, Mainz, Germany
18
10.10 am

Innovative self-assembling peptide biomaterial for targeted prostate cancer drug delivery

Bárbara Matos
INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Porto, Portugal, Porto, Portugal i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal, Porto, Portugal
19
10.25 am

De novo design of transmembrane beta-barrel nanopores with defined shapes and functions

Anastassia Vorobieva
Vrije Universiteit Brussel, Bruxelles, Belgium
0
10.50 am

Coffee break


20
11.20 am

Remarkable structural plasticity and tunability of the potyviral coat protein

Marjetka Podobnik
Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
21
11.45 am

Identifying allosteric inhibitors of human histone deacetylase 8 (HDAC8)

Adrian Velazquez-Campoy
Institute BIFI - LACRIMA, University of Zaragoza, Zaragoza, Spain Department of Biochemistry and Molecular and Cell Biology, University of Zaragoza, Zaragoza, Spain
22
12.00 pm

Leveraging the E222Q replacement to generate novel reversibly switchable fluorescent Aequorea victoria proteins for super-resolution imaging

Ranieri Bizzarri
NEST, Istituto Nanoscienze (CNR-NANO) and Scuola Normale Superiore, Consiglio Nazionale delle Ricerche, Pisa, Italy Department of Surgical, medical, Molecular Pathology and Critical Care medicine, University of Pisa, Pisa, Italy
23
12.15 pm

Designing, developing, and evaluating a protein-peptide binding system for fundamental biophysics and biophysical instrument evaluation

Mark Williams
BiophysX Centre, Birkbeck, University of London, London, United Kingdom
24
12.30 pm

Understanding Carbonic Anhydrase Inhibition: Structural and Thermodynamic Insights

Vaida Paketuryte-Latve
departmant of biothermodynamics and drugs design, Vilnius University, Vilnius, Lithuania
25
12.45 pm

Pushing The Boundaries in Biomolecular Interaction Analysis with the Creoptix WAVE system

Aymeric Audfray
PhD, Field Application Scientist, Malvern Panalytical, France
26
12.55 pm

Advancing Molecular Interaction Analysis with FIDA Technology

Marion Albasini
Fida Biosystems ApS, Soborg, Denmark
Lunch
1.05 pm-2.15 pm
Artificial intelligence, computational approaches and data analysis
2.15 pm-6.15 pm
Chair: Javier Sancho, University of Zaragoza, Spain
27
2.15 pm

De novo design of new-to-nature immunoglobulin-like proteins using deep learning

Enrique Marcos Benteo
Institute of Molecular Biology of Barcelona, Barcelone, Spain
28
2.40 pm

Charting γ-secretase substrates by explainable AI 

Dmitrij Frishman
Technical University of Munich, Freising, Germany
29
2.55 pm

Protein-Ligan Binding Database (PLBD) of Affinities and Enthalpies for AI-ML in Drug Discovery

Daumantas Matulis
Biothermodynamics and Drug Design, Vilnius University, Vilnius, Lithuania
30
3.10 pm

AFMfit : Deciphering conformational dynamics in AFM data using fast nonlinear NMA and FFT-based search

Rémi Vuillemot
Laboratoire Jean Kuntzmann - CNRS, France
31
3.25 pm

Seeing Structure, Seeking Function: Enabling Molecular Insight with Rigaku

Kanda Hiroyuki
Senior Director & Global Product Leader, Life Science Product Division, Rigaku Corporation, Tokyo, Japan
32
3.35 pm

MAGNA™: A novel single molecule approach for the real-time analysis of biomolecular interactions using magnetic force spectroscopy

Elie Hammam
Field Application Scientist, Depixus SAS, France
0
3.45 pm

Coffee break


33
4.15 pm

The interplay of key parameters in the transport process of small synthetic chloride carriers

Sara Boi
University of Cagliari, Monserrato, Italy
34
4.30 pm

Managing raw biophysical data under the Molecular Biophysics Database

Jan Dohnálek
Laboratory of Structure and Function of Biomolecules, MoB-IBT, Institute of Biotechnology of the Czech Academy of Sciences, Vestec, Czech Republic
35
4.55 pm

KinGenie, an online, user-friendly tool to analyse surface- and solution-based binding kinetics

Osvaldo Burastero
European Molecular Biology Laboratory, Hamburg, Germany
36
5.10 pm

Identification of aggregation prone regions in amyloidogenic proteins by combining multidimensional predictions and molecular dynamics

Julien Mignon
Department of Chemistry, Laboratoire de Chimie Physique des Biomolécules, University of Namur, Namur, Belgium
37
5.25 pm

Meet Aunty, the Queen of high throughput protein stability


38
5.35 pm

Visualizing the unseen: conversation on a journey through Art and Science

Giorgio Giardina
Sapienza University, Rome, Italy
2nd Poster session
6.15 pm-7.55 pm
Thursday, June 12, 2025
Welcome coffee
08.30 am-09.00 am
Molecular biophysics In situ/in vivo and in biomimetic environments
09.00 am-1.05 pm
Chair: Lorena Redondo-Morata, Dynamics and nanoenvironment of biological membranes, France
39
09.00 am

A universal scaling law for mitotic spindles across eukaryotes driven by chromosome crowding

Iva Tolic
RBI Zagreb, Zagreb, Croatia
40
09.40 am

Membrane damage by α-synuclein is preceded by an increase in lipid packing energy

Claudio Canale
Dept. of Physics, University of Genoa, Genova, Italy
41
09.55 am

Functional reconstitution of Mfn2-Mediated Fusion in PE-Enriched Vesicles

Ivan Lopez Montero
Universidad Complutense de Madrid, Madrid, Spain
42
10.10 am

Resolving individual multi-molecular interactions in living cells 

Maria Garcia-Parajo
Institute of Photonic Sciences, Barcelone, Spain
43
10.35 am

Dynamic Equilibrium of a Bacterial Chaperone: Cellular Factors Promote the Closed Conformation

Angeliki Giannouli
Department of Chemistry, University of Crete, Heraklion, Greece BIP, Bioénergétique et Ingénierie des Protéines, Aix Marseille University, Marseille, France
0
10.50 am

Group photo


0
11.00 am

Coffee break


44
11.30 am

Unraveling Lipid Membrane Dynamics and Phase Behavior Using AFM

Lorena Redondo-Morata
Aix-Marseille University, INSERM, DyNaMo, Turing centre for living systems, Marseille, France
45
11.55 am

Focal Molography - A Label-Free Platform for Real-Time Analysis of Molecular Interactions in Living Cells

Andreas Frutiger
lino Biotech AG, Adliswil, Switzerland
46
12.10 pm

MEASURING BACTERIAL OXYGEN CONSUMPTION RATE TO PROBE METABOLIC SIGNATURE AND ANTIMICROBIAL SUSCEPTIBILITY

Serena Rinaldo
Biochemical Sciences, Sapienza University of Rome, Rome, Italy
47
12.25 pm

Assessment of the colloidal stability of carbon nano-onions-DNA hybrid materials for further nanomedicine applications

Julia Mónica Requena Ramirez
Departamento de Química Inorgánica, Instituto De Ciencia Molecular (Universidad De Valencia), Valencia, Spain
48
12.40 pm

Plant vs Dairy protein stabilised cappuccino foams: how protein and hydrocolloid conformational changes affect foam stability.

Timothy Wooster
Institute of Food Sciences, Nestlé Research, Lausanne, Switzerland
49
12.55 pm

Biophysical investigation of antibodies from high-throughput screening to in-depth characterization on cells

Stephane Pinhal
Bruker Daltonics GmbH & Co. KG, Germany
Lunch
1.05 pm-2.15 pm
Molecular biophysics to address societal challenges (climate change, infectious or degenerative diseases, ...)
2.15 pm-6.05 pm
Chair: Adriana Erica Miele, Université Claude Bernard Lyon 1, France
50
2.15 pm

Atomic Force Microscopy: Unveiling Tuberculosis and Malaria Through Imaging and Force Spectroscopy

Thomas Gutsmann
Biophysics, Research Center Borstel, Borstel, Germany Centre for Strctural Systems Biology, Hamburg, Germany
51
2.40 pm

How do plants sense temperature?
Nanostructure characterization of biological hydrogels formed by the prion-like domain EARLY FLOWERING 3 using SAXS

Mark Tully
BM29 BioSAXS, ESRF, Grenoble, France
52
2.55 pm

The complex choreography of gelsolin, a master regulator of cytoskeleton

Loic Girois
MolBD3, istituto di biofisica IBF Milano, Milano, Italy
53
3.10 pm

Circular dichroism spectroscopic study on the metal ion selectivity of the AfArsR model peptide

Bela Gyurcsik
Department of Molecular and Analytical Chemistry, University of Szeged, Hungary, Szeged, Hungary
54
3.25 pm

Biophysical characterisation of oligomeric states of pyroglutamate-modified alpha-synuclein

Alexandra Bluhm
University of Leipzig, Leipzig, Germany
55
3.40 pm

Fluidic Sciences

James Wilkinson
Fluidic Sciences, Royston, United Kingdom
56
3.50 pm

Explore the unknown, Choose SPR and Biacore™ systems

Claire Shepherd
Global Product Manager – Biacore Consumables - Cytiva, France
0
4.00 pm

Coffee break


57
4.30 pm

Pathogenicity of enterobacterial strains isolated from urinary tract infections in BENIN and searching for plant-derived bioactive molecules (Zoom conference)

Funke Faizatou Assouma
faculty of science and technology, laboratory of biology and molecular typing in microbiology, University of Abomey Calavi, Seme Podji, Benin
58
4.45 pm

Subsite binding in the yin-and-yang Bacteroides thetaiotaomicron sialidase at 1.5 Å resolution

Julie Bouckaert
Unité de Glycobiologie Structurale et Fonctionnelle - UGSF, UMR 8576 CNRS & Lille University, Villeneuve D'ascq, France
59
5.00 pm

Conductive protein-based biomaterials: from the design to the application

Paolo Blesio
Biomolecular Nanotechnology group, Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research And Technology Alliance (brta), Paseo De Miramon 194, Donostia/san Sebastian. 20014, Spain
60
5.15 pm

Insights into the structure-activity relationship of SMAD4 variants associated with Myhre syndrome

Carles Torner
Institute for Research in Biomedicine, Barcelona, Spain
61
5.30 pm

Unlocking Molecular Truths with SEC-MALS for Proteins, RNA, and Nanobodies

Philippe Boniteau
Application Scientist at Waters | Wyatt Technology, United States
62
5.40 pm

Molecular biophysics meets parasitology: how to select biomarkers to test schistosomiasis infections

Adriana Erica Miele
UMR 5280 Institut des Sciences Analytiques, Université Claude Bernard Lyon 1, Villeurbanne, France
3rd Poster session
6.05 pm-7.00 pm
Conference dinner
7.45 pm-11.00 pm
Friday, June 13, 2025
Welcome coffee
08.30 am-09.15 am
Single molecule/single particle biophysics
09.15 am-12.45 pm
Chairs: Patrick England, Institut Pasteur, France - Wouter Roos, Rijksuniversiteit Groningen, The Netherlands
63
09.15 am

The complex task of simplifying biology

Petra Schwille
Director, Cellular and Molecular Biophysics Max Planck Institute of Biochemistry, Martinsried, Germany
64
09.55 am

Exploring single molecule unbinding near to equilibrium by acoustic force spectroscopy

Claire Valotteau
DyNaMo, Inserm, Aix-Marseille Université, Marseille, France DyNaMo, CNRS, Marseille, France
65
10.10 am

Manipulation of large protein complexes with DNA forceps: Deciphering binding mechanisms and testing molecular heterogeneity

Charlie Gosse
Institut de Biologie de l'Ecole Normale Supérieure, CNRS, Paris, France
66
10.25 am

Tracking and tracing complex DNA structures critical to human health

Alice Pyne
University of Sheffield, Sheffield, United Kingdom
67
10.50 am

Modifying Norovirus capsid assembly through N-terminal mutations.

Jennifer Rothe
Center for Structural Systems Biology, Hamburg, Germany University of Groningen, Groningen, The Netherlands
0
11.05 am

Coffee break


68
11.35 am

Single-molecule optical tweezers applied to transmembrane proteins

Katarzyna (kasia) Tych
Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands
69
12.00 pm

Single-molecule and multiscale fluorescence imaging to investigate PD-L1 dynamics and its association with lipid raft in Non-Small Cell Lung Cancer cells

Simone Civita
Department of Surgical, Medical and Molecular Pathology, and Critical Care Medicine, University of Pisa, Pisa, Italy
70
12.15 pm

Molecular mechanisms of Hepatitis B virus capsid protein interactions with the viral genome

Yanping Gong
Moleculaire Biofysica, Zernike Instituut, Rijksuniversiteit Groningen, Groningen, The Netherlands
71
12.30 pm

Disorder, assembly and function: the molecular behavior of disordered translation factors across multifaceted self-association landscape

Mikayel Aznauryan
ARNA U1212, IECB, INSERM - Universite de Bordeaux, Pessac, France
Concluding remarks/end of conference
12.45 pm-1.00 pm


 

 

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